Jigsaw has disappeared. Along with his new apprentice Amanda, the puppet-master behind the cruel, intricate games that have terrified a community and baffled police has once again eluded capture and vanished. While city detective scrambles to locate him, Doctor Lynn Denlon and Jeff Reinhart are unaware that they are about to become the latest pawns on his vicious chessboard.
- Genre: Horror, Thriller, Crime
- Studio: Twisted Pictures, Evolution Entertainment, Lionsgate
- Keyword: brain tumor, suffocation, sadism, torture, survival horror, death match, mutilation, mind game
- Cast: Tobin Bell, Shawnee Smith, Angus Macfadyen, Bahar Soomekh, Donnie Wahlberg, Dina Meyer